Nanba et al reported that 7 of 12 patients with liver cancer responded to a combination of Grifola frondosa fruiting body (4-6g/day) and purified polysaccharide extract (MD fraction – 40-150mg/day),1. Studies using implanted sarcoma 180 as a model for liver cancer have shown inhibition of tumour rates of 52.8%, 56.6%...Read more
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A recent meta-analysis of 3 clinical trials in Japan with 1,094 patients showed clear benefit from PSK supplementation (3.0g/day) in improving both survival and disease-free survival in cases of curatively resected colorectal cancer1,2. Chihara et al also report excellent results from a 4 year follow-up of Lentinan in phase III...Read more
Schizophyllan (Sizofiran), a polysaccharide extract of Schizophyllan commune, is licensed in Japan for the treatment of cervical cancer and, in a 5-year multi-centre study, has been shown to significantly extend time to recurrence and improve survival rates in patients with stage II cervical cancer but not in those with stage...Read more
Trametes versicolor polysaccharide extracts show impressive benefits in cases of lung cancer. In a 1993 study on patients with stage I-III non-small cell lung cancer treated with radiotherapy and PSK, PSK extended 5-yr survival 2-4x for all stages with maximum benefit in patients over the age of 70 and for...Read more
Ganoderma lucidum has been identified as a promising agent for prostate cancer with in vitro evidence showing inhibition of hormone dependent and independent prostate cancer cells through multiple pathways, including binding to androgen receptor, inhibition of the active transcription factors: NF-kB and AP-1, inhibition of urokinase-type plasminogen activator (uPA) and...Read more
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