Ganoderma lucidum shows excellent results in the management of allergic rhinitis, its polysaccharides suppressing the pro-inflammatory, Th2 mediated immune state responsible for the hypersensitivity to the particular allergen(s) while several of its triterpenoid ganoderic and lucidenic acids have direct anti-inflammatory and anti-histamine action1-4. It thus addresses both the symptoms and the underlying imbalance of the condition and can be used in a prophylactic or therapeutic mode. 1. Anti-allergic constituents in the culture medium of Ganoderma lucidum. (I). Inhibitory effect of oleic acid on histamine release. Tasaka K, Akagi M, Miyoshi K, Mio M, Makino T. Inflammation Research. 1988;23(3-4):153-6
2. Anti-allergic constituents in the culture medium of
Ganoderma lucidum. (II). The inhibitory effect of
cyclooctasulfur on histamine release. Tasaka K, Mio M,
Izushi K, Akagi M, Makino T. Inflammation Research.
3. Effectiveness of Dp2 nasal therapy for Dp2- induced airway
inflammation in mice: using oral Ganoderma lucidum as an
immunomodulator. Liu Y.H, Tsai C.F, Kao M.C, Lai Y.L, Tsai
J.J. J Microbiol Immunol Infect. 2003;36(4):236-428.
4. The use of Ganoderma lucidum (Reishi) in the management
of Histamine-mediated allergic responses. Powell M.
Nutritional Practitioner Magazine. October 2004